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Implementing an X-ray validation pipeline for the Protein Data Bank

There is an increasing realisation that the quality of the biomacromolecular structures deposited in the Protein Data Bank (PDB) archive needs to be assessed critically using established and powerful validation methods. The Worldwide Protein Data Bank (wwPDB) organization has convened several Valida...

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Detalles Bibliográficos
Autores principales: Gore, Swanand, Velankar, Sameer, Kleywegt, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322607/
https://www.ncbi.nlm.nih.gov/pubmed/22505268
http://dx.doi.org/10.1107/S0907444911050359
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author Gore, Swanand
Velankar, Sameer
Kleywegt, Gerard J.
author_facet Gore, Swanand
Velankar, Sameer
Kleywegt, Gerard J.
author_sort Gore, Swanand
collection PubMed
description There is an increasing realisation that the quality of the biomacromolecular structures deposited in the Protein Data Bank (PDB) archive needs to be assessed critically using established and powerful validation methods. The Worldwide Protein Data Bank (wwPDB) organization has convened several Validation Task Forces (VTFs) to advise on the methods and standards that should be used to validate all of the entries already in the PDB as well as all structures that will be deposited in the future. The recommendations of the X-ray VTF are currently being implemented in a software pipeline. Here, ongoing work on this pipeline is briefly described as well as ways in which validation-related information could be presented to users of structural data.
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spelling pubmed-33226072012-04-16 Implementing an X-ray validation pipeline for the Protein Data Bank Gore, Swanand Velankar, Sameer Kleywegt, Gerard J. Acta Crystallogr D Biol Crystallogr Research Papers There is an increasing realisation that the quality of the biomacromolecular structures deposited in the Protein Data Bank (PDB) archive needs to be assessed critically using established and powerful validation methods. The Worldwide Protein Data Bank (wwPDB) organization has convened several Validation Task Forces (VTFs) to advise on the methods and standards that should be used to validate all of the entries already in the PDB as well as all structures that will be deposited in the future. The recommendations of the X-ray VTF are currently being implemented in a software pipeline. Here, ongoing work on this pipeline is briefly described as well as ways in which validation-related information could be presented to users of structural data. International Union of Crystallography 2012-04-01 2012-03-16 /pmc/articles/PMC3322607/ /pubmed/22505268 http://dx.doi.org/10.1107/S0907444911050359 Text en © Gore et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Papers
Gore, Swanand
Velankar, Sameer
Kleywegt, Gerard J.
Implementing an X-ray validation pipeline for the Protein Data Bank
title Implementing an X-ray validation pipeline for the Protein Data Bank
title_full Implementing an X-ray validation pipeline for the Protein Data Bank
title_fullStr Implementing an X-ray validation pipeline for the Protein Data Bank
title_full_unstemmed Implementing an X-ray validation pipeline for the Protein Data Bank
title_short Implementing an X-ray validation pipeline for the Protein Data Bank
title_sort implementing an x-ray validation pipeline for the protein data bank
topic Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322607/
https://www.ncbi.nlm.nih.gov/pubmed/22505268
http://dx.doi.org/10.1107/S0907444911050359
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