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East Africans in Sweden Have a High Risk for Type 1 Diabetes

OBJECTIVE: To investigate the prevalence of type 1 diabetes in children with an origin in Sub-Saharan Africa in Sweden. RESEARCH DESIGN AND METHODS: Nationwide register study based on retrieved prescriptions of insulin during 2009 in children aged 0–18 years. The study population consisted of 35,756...

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Detalles Bibliográficos
Autores principales: Hjern, Anders, Söderström, Ulf, Åman, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322724/
https://www.ncbi.nlm.nih.gov/pubmed/22301119
http://dx.doi.org/10.2337/dc11-1536
Descripción
Sumario:OBJECTIVE: To investigate the prevalence of type 1 diabetes in children with an origin in Sub-Saharan Africa in Sweden. RESEARCH DESIGN AND METHODS: Nationwide register study based on retrieved prescriptions of insulin during 2009 in children aged 0–18 years. The study population consisted of 35,756 children in families with an origin in Sub-Saharan Africa and 1,666,051 children with native Swedish parents. RESULTS: The odds ratio (OR) for insulin medication in Swedish-born children in families originating in East Africa was 1.29 (95% CI 1.02–1.63) compared with offspring of native Swedish parents, after adjustment for age and sex, and less common in children who themselves were born in East Africa: 0.50 (0.34–0.73). Offspring of parents from other parts of Sub-Saharan Africa had a comparatively low risk for insulin medication. CONCLUSIONS: This study indicates that Swedish-born children with an origin in East Africa have a high risk of type 1 diabetes.