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Hospital-reported Pneumococcal Susceptibility to Penicillin

Geographic variation in drug susceptibility among isolates of Streptococcus pneumoniae has influenced national treatment guidelines for community-acquired pneumonia. Whether individual hospital susceptibility data provide reliable and valid information for providers is unclear. We examined the geogr...

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Autores principales: Metlay, Joshua P., Branas, Charles C., Fishman, Neil O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322741/
https://www.ncbi.nlm.nih.gov/pubmed/15078597
http://dx.doi.org/10.3201/eid1001.030140
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author Metlay, Joshua P.
Branas, Charles C.
Fishman, Neil O.
author_facet Metlay, Joshua P.
Branas, Charles C.
Fishman, Neil O.
author_sort Metlay, Joshua P.
collection PubMed
description Geographic variation in drug susceptibility among isolates of Streptococcus pneumoniae has influenced national treatment guidelines for community-acquired pneumonia. Whether individual hospital susceptibility data provide reliable and valid information for providers is unclear. We examined the geographic and temporal variability in hospital-reported rates of pneumococcal susceptibility. We surveyed all 52 hospitals that provided acute adult care in the five counties surrounding Philadelphia and collected data on levels of penicillin susceptibility among all pneumococcal blood isolates from 1998 to 2000. In 1998, pneumococcal nonsusceptibility to penicillin varied from 0% to 67% of all blood isolates across the 33 hospitals with >10 isolates in that year. Hospital location did not correlate with the level of reported pneumococcal susceptibility (p = 0.8). In addition, correlations were not significant in reported pneumococcal susceptibility to penicillin within individual hospitals during the 3 years.
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spelling pubmed-33227412012-04-16 Hospital-reported Pneumococcal Susceptibility to Penicillin Metlay, Joshua P. Branas, Charles C. Fishman, Neil O. Emerg Infect Dis Research Geographic variation in drug susceptibility among isolates of Streptococcus pneumoniae has influenced national treatment guidelines for community-acquired pneumonia. Whether individual hospital susceptibility data provide reliable and valid information for providers is unclear. We examined the geographic and temporal variability in hospital-reported rates of pneumococcal susceptibility. We surveyed all 52 hospitals that provided acute adult care in the five counties surrounding Philadelphia and collected data on levels of penicillin susceptibility among all pneumococcal blood isolates from 1998 to 2000. In 1998, pneumococcal nonsusceptibility to penicillin varied from 0% to 67% of all blood isolates across the 33 hospitals with >10 isolates in that year. Hospital location did not correlate with the level of reported pneumococcal susceptibility (p = 0.8). In addition, correlations were not significant in reported pneumococcal susceptibility to penicillin within individual hospitals during the 3 years. Centers for Disease Control and Prevention 2004-01 /pmc/articles/PMC3322741/ /pubmed/15078597 http://dx.doi.org/10.3201/eid1001.030140 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Metlay, Joshua P.
Branas, Charles C.
Fishman, Neil O.
Hospital-reported Pneumococcal Susceptibility to Penicillin
title Hospital-reported Pneumococcal Susceptibility to Penicillin
title_full Hospital-reported Pneumococcal Susceptibility to Penicillin
title_fullStr Hospital-reported Pneumococcal Susceptibility to Penicillin
title_full_unstemmed Hospital-reported Pneumococcal Susceptibility to Penicillin
title_short Hospital-reported Pneumococcal Susceptibility to Penicillin
title_sort hospital-reported pneumococcal susceptibility to penicillin
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322741/
https://www.ncbi.nlm.nih.gov/pubmed/15078597
http://dx.doi.org/10.3201/eid1001.030140
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