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Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells
Heparan sulfate proteoglycans, present on cell surfaces and in the extracellular matrix, interact with growth factors and morphogens to influence growth and differentiation of cells. The sulfation pattern of the heparan sulfate chains formed during biosynthesis in the Golgi compartment will determin...
Autores principales: | Forsberg, Maud, Holmborn, Katarina, Kundu, Soumi, Dagälv, Anders, Kjellén, Lena, Forsberg-Nilsson, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322844/ https://www.ncbi.nlm.nih.gov/pubmed/22298785 http://dx.doi.org/10.1074/jbc.M111.337030 |
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