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Combining Clinical and Epidemiologic Features for Early Recognition of SARS

Early recognition and rapid initiation of infection control precautions are currently the most important strategies for controlling severe acute respiratory syndrome (SARS). No rapid diagnostic tests currently exist that can rule out SARS among patients with febrile respiratory illnesses. Clinical f...

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Detalles Bibliográficos
Autores principales: Jernigan, John A., Low, Donald E., Helfand, Rita F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322910/
https://www.ncbi.nlm.nih.gov/pubmed/15030706
http://dx.doi.org/10.3201/eid1002.030741
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author Jernigan, John A.
Low, Donald E.
Helfand, Rita F.
author_facet Jernigan, John A.
Low, Donald E.
Helfand, Rita F.
author_sort Jernigan, John A.
collection PubMed
description Early recognition and rapid initiation of infection control precautions are currently the most important strategies for controlling severe acute respiratory syndrome (SARS). No rapid diagnostic tests currently exist that can rule out SARS among patients with febrile respiratory illnesses. Clinical features alone cannot with certainty distinguish SARS from other respiratory illnesses rapidly enough to inform early management decisions. A balanced approach to screening that allows early recognition of SARS without unnecessary isolation of patients with other respiratory illnesses will require clinicians not only to look for suggestive clinical features but also to routinely seek epidemiologic clues suggestive of SARS coronavirus exposure. Key epidemiologic risk factors include 1) exposure to settings where SARS activity is suspected or documented, or 2) in the absence of such exposure, epidemiologic linkage to other persons with pneumonia (i.e., pneumonia clusters), or 3) exposure to healthcare settings. When combined with clinical findings, these epidemiologic features provide a possible strategic framework for early recognition of SARS.
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spelling pubmed-33229102012-04-17 Combining Clinical and Epidemiologic Features for Early Recognition of SARS Jernigan, John A. Low, Donald E. Helfand, Rita F. Emerg Infect Dis Perspective Early recognition and rapid initiation of infection control precautions are currently the most important strategies for controlling severe acute respiratory syndrome (SARS). No rapid diagnostic tests currently exist that can rule out SARS among patients with febrile respiratory illnesses. Clinical features alone cannot with certainty distinguish SARS from other respiratory illnesses rapidly enough to inform early management decisions. A balanced approach to screening that allows early recognition of SARS without unnecessary isolation of patients with other respiratory illnesses will require clinicians not only to look for suggestive clinical features but also to routinely seek epidemiologic clues suggestive of SARS coronavirus exposure. Key epidemiologic risk factors include 1) exposure to settings where SARS activity is suspected or documented, or 2) in the absence of such exposure, epidemiologic linkage to other persons with pneumonia (i.e., pneumonia clusters), or 3) exposure to healthcare settings. When combined with clinical findings, these epidemiologic features provide a possible strategic framework for early recognition of SARS. Centers for Disease Control and Prevention 2004-02 /pmc/articles/PMC3322910/ /pubmed/15030706 http://dx.doi.org/10.3201/eid1002.030741 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Perspective
Jernigan, John A.
Low, Donald E.
Helfand, Rita F.
Combining Clinical and Epidemiologic Features for Early Recognition of SARS
title Combining Clinical and Epidemiologic Features for Early Recognition of SARS
title_full Combining Clinical and Epidemiologic Features for Early Recognition of SARS
title_fullStr Combining Clinical and Epidemiologic Features for Early Recognition of SARS
title_full_unstemmed Combining Clinical and Epidemiologic Features for Early Recognition of SARS
title_short Combining Clinical and Epidemiologic Features for Early Recognition of SARS
title_sort combining clinical and epidemiologic features for early recognition of sars
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322910/
https://www.ncbi.nlm.nih.gov/pubmed/15030706
http://dx.doi.org/10.3201/eid1002.030741
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