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Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong
We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322939/ https://www.ncbi.nlm.nih.gov/pubmed/15030696 http://dx.doi.org/10.3201/eid1002.030452 |
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author | Wong, Tze-wai Lee, Chin-kei Tam, Wilson Lau, Joseph Tak-fai Yu, Tak-sun Lui, Siu-fai Chan, Paul K.S. Li, Yuguo Bresee, Joseph S. Sung, Joseph J.Y. Parashar, Umesh D. |
author_facet | Wong, Tze-wai Lee, Chin-kei Tam, Wilson Lau, Joseph Tak-fai Yu, Tak-sun Lui, Siu-fai Chan, Paul K.S. Li, Yuguo Bresee, Joseph S. Sung, Joseph J.Y. Parashar, Umesh D. |
author_sort | Wong, Tze-wai |
collection | PubMed |
description | We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visited the index patient’s ward, including 16 students with SARS and 50 healthy students. The risk of contracting SARS was sevenfold greater among students who definitely visited the index case’s cubicle than in those who did not (10/27 [41%] versus 1/20 [5%], relative risk [RR] 7.4; 95% confidence interval [CI] 1.0 to 53.3). Illness rates increased directly with proximity of exposure to the index case. However, four of eight students who were in the same cubicle, but were not within 1 m of the index case-patient, contracted SARS. Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread. Transmission through fomites or small aerosols cannot be ruled out. |
format | Online Article Text |
id | pubmed-3322939 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-33229392012-04-17 Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong Wong, Tze-wai Lee, Chin-kei Tam, Wilson Lau, Joseph Tak-fai Yu, Tak-sun Lui, Siu-fai Chan, Paul K.S. Li, Yuguo Bresee, Joseph S. Sung, Joseph J.Y. Parashar, Umesh D. Emerg Infect Dis Research We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visited the index patient’s ward, including 16 students with SARS and 50 healthy students. The risk of contracting SARS was sevenfold greater among students who definitely visited the index case’s cubicle than in those who did not (10/27 [41%] versus 1/20 [5%], relative risk [RR] 7.4; 95% confidence interval [CI] 1.0 to 53.3). Illness rates increased directly with proximity of exposure to the index case. However, four of eight students who were in the same cubicle, but were not within 1 m of the index case-patient, contracted SARS. Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread. Transmission through fomites or small aerosols cannot be ruled out. Centers for Disease Control and Prevention 2004-02 /pmc/articles/PMC3322939/ /pubmed/15030696 http://dx.doi.org/10.3201/eid1002.030452 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Wong, Tze-wai Lee, Chin-kei Tam, Wilson Lau, Joseph Tak-fai Yu, Tak-sun Lui, Siu-fai Chan, Paul K.S. Li, Yuguo Bresee, Joseph S. Sung, Joseph J.Y. Parashar, Umesh D. Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong |
title | Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong |
title_full | Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong |
title_fullStr | Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong |
title_full_unstemmed | Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong |
title_short | Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong |
title_sort | cluster of sars among medical students exposed to single patient, hong kong |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322939/ https://www.ncbi.nlm.nih.gov/pubmed/15030696 http://dx.doi.org/10.3201/eid1002.030452 |
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