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Functional imaging: what evidence is there for its utility in clinical trials of targeted therapies?
Key issues in early clinical trials of targeted agents include the determination of target inhibition, rational patient selection based on pre-treatment tumour characteristics, and assessment of tumour response in the absence of actual shrinkage. There is accumulating evidence that functional imagin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322943/ https://www.ncbi.nlm.nih.gov/pubmed/22281664 http://dx.doi.org/10.1038/bjc.2011.579 |