Cargando…

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid

Bioactive mediators derived from omega-3 eicosapentaenoic acid (EPA) elicit potent anti-inflammatory actions. Here, we identified novel EPA metabolites, including 8,18-dihydroxyeicosapentaenoic acid (8,18-diHEPE), 11,18-diHEPE, 12,18-diHEPE, and 17,18-diHEPE from 18-HEPE. Unlike resolvins E1 and E2,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Isobe, Yosuke, Arita, Makoto, Matsueda, Shinnosuke, Iwamoto, Ryo, Fujihara, Takuji, Nakanishi, Hiroki, Taguchi, Ryo, Masuda, Koji, Sasaki, Kenji, Urabe, Daisuke, Inoue, Masayuki, Arai, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Lipids
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322993/ https://www.ncbi.nlm.nih.gov/pubmed/22275352 http://dx.doi.org/10.1074/jbc.M112.340612

Ejemplares similares

Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells
por: Shindou, Hideo, et al.
Publicado: (2017)

Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response
por: Ariyama, Hiroyuki, et al.
Publicado: (2010)

Rapid Production of Platelet-activating Factor Is Induced by Protein Kinase Cα-mediated Phosphorylation of Lysophosphatidylcholine Acyltransferase 2 Protein
por: Morimoto, Ryo, et al.
Publicado: (2014)

Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut
por: Kunisawa, Jun, et al.
Publicado: (2015)

Identification of Plant-like Galactolipids in Chromera velia, a Photosynthetic Relative of Malaria Parasites
por: Botté, Cyrille Y., et al.
Publicado: (2011)

Purification, Identification, and Cloning of Lysoplasmalogenase, the Enzyme That Catalyzes Hydrolysis of the Vinyl Ether Bond of Lysoplasmalogen
por: Wu, Lai-Chu, et al.
Publicado: (2011)

Antioxidant-rich spice added to hamburger meat during cooking results in reduced meat, plasma, and urine malondialdehyde concentrations(1)(2)(3)(4)
por: Li, Zhaoping, et al.
Publicado: (2010)

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
por: He, Shaoqing, et al.
Publicado: (2010)

Randomized controlled study of the effect of a butter naturally enriched in trans fatty acids on blood lipids in healthy women(1)(2)(3)
por: Lacroix, Émilie, et al.
Publicado: (2012)

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease
por: Huang, Yongcheng, et al.
Publicado: (2011)

Ceramide Kinase Regulates the Production of Tumor Necrosis Factor α (TNFα) via Inhibition of TNFα-converting Enzyme
por: Lamour, Nadia F., et al.
Publicado: (2011)

Functional and Topological Analysis of Yeast Acyl-CoA:Diacylglycerol Acyltransferase 2, an Endoplasmic Reticulum Enzyme Essential for Triacylglycerol Biosynthesis
por: Liu, Qin, et al.
Publicado: (2011)

Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP: CHIMERAS AND POINT MUTANTS IDENTIFY INTRACELLULAR AMINO-TERMINAL RESIDUES INVOLVED IN LIPID REGULATION OF P2X1 RECEPTORS
por: Allsopp, Rebecca C., et al.
Publicado: (2010)

Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis Are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1
por: Calandria, Jorgelina M., et al.
Publicado: (2012)

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation
por: Thomas, Christopher P., et al.
Publicado: (2010)

Metabolic and Transcriptional Responses of Glycerolipid Pathways to a Perturbation of Glycerol 3-Phosphate Metabolism in Arabidopsis
por: Shen, Wenyun, et al.
Publicado: (2010)

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages
por: Aflaki, Elma, et al.
Publicado: (2011)

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase
por: Chandak, Prakash G., et al.
Publicado: (2010)

Kdo(2)-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy
por: Sims, Kacee, et al.
Publicado: (2010)

Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation
por: Kosenko, Tanja, et al.
Publicado: (2013)

Identification of a Mammalian-type Phosphatidylglycerophosphate Phosphatase in the Eubacterium Rhodopirellula baltica
por: Teh, Phildrich G., et al.
Publicado: (2013)

Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase
por: Rengachari, Srinivasan, et al.
Publicado: (2013)

Effects of a Disrupted Blood-Brain Barrier on Cholesterol Homeostasis in the Brain
por: Saeed, Ahmed A., et al.
Publicado: (2014)

High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F(2α) concentrations relative to a control high–oleic acid meal: a randomized controlled trial(1)(2)(3)(4)
por: Purcell, Robert, et al.
Publicado: (2014)

Biosynthesis and Translocation of Unsulfated Acyltrehaloses in Mycobacterium tuberculosis
por: Belardinelli, Juan Manuel, et al.
Publicado: (2014)

Vitellogenin Receptor Mutation Leads to the Oogenesis Mutant Phenotype “scanty vitellin” of the Silkworm, Bombyx mori
por: Lin, Ying, et al.
Publicado: (2013)

Mechanisms Responsible for the Compositional Heterogeneity of Nascent High Density Lipoprotein
por: Lund-Katz, Sissel, et al.
Publicado: (2013)

Transcription Factor Reb1p Regulates DGK1-encoded Diacylglycerol Kinase and Lipid Metabolism in Saccharomyces cerevisiae
por: Qiu, Yixuan, et al.
Publicado: (2013)

Distinct Roles of the Phosphatidate Phosphatases Lipin 1 and 2 during Adipogenesis and Lipid Droplet Biogenesis in 3T3-L1 Cells
por: Sembongi, Hiroshi, et al.
Publicado: (2013)

Plant Acyl-CoA:Lysophosphatidylcholine Acyltransferases (LPCATs) Have Different Specificities in Their Forward and Reverse Reactions
por: Lager, Ida, et al.
Publicado: (2013)

The Endoplasmic Reticulum Coat Protein II Transport Machinery Coordinates Cellular Lipid Secretion and Cholesterol Biosynthesis
por: Fryer, Lee G. D., et al.
Publicado: (2014)

Crystal Structures of Leukotriene C(4) Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM
por: Niegowski, Damian, et al.
Publicado: (2014)

Novel Keto-phospholipids Are Generated by Monocytes and Macrophages, Detected in Cystic Fibrosis, and Activate Peroxisome Proliferator-activated Receptor-γ
por: Hammond, Victoria J., et al.
Publicado: (2012)

Long-chain PUFA supplementation in rural African infants: a randomized controlled trial of effects on gut integrity, growth, and cognitive development(1)(2)(3)
por: van der Merwe, Liandré F, et al.
Publicado: (2013)

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling
por: Hofer, Peter, et al.
Publicado: (2015)

Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1
por: Chauhan, Neha, et al.
Publicado: (2016)

Effect of mastication on lipid bioaccessibility of almonds in a randomized human study and its implications for digestion kinetics, metabolizable energy, and postprandial lipemia(1)(2)(3)(4)
por: Grundy, Myriam ML, et al.
Publicado: (2015)

Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins
por: Smagris, Eriks, et al.
Publicado: (2016)

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
por: Heier, Christoph, et al.
Publicado: (2016)

A Peptide Derived from G(0)/G(1) Switch Gene 2 Acts as Noncompetitive Inhibitor of Adipose Triglyceride Lipase
por: Cerk, Ines K., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1nbqdrd42meoqg19ogrkioa4ii