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Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins
Limited data identify the risk factors for infection with Enterobacteriaceae resistant to third-generation cephalosporins among residents of long-term-care facilities. Using a nested case-control study design, nursing home residents with clinical isolates of Enterobacteriaceae resistant to third-gen...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323163/ https://www.ncbi.nlm.nih.gov/pubmed/15207056 http://dx.doi.org/10.3201/eid1006.030662 |
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author | Sandoval, Carolyn Walter, Stephen D. McGeer, Allison Simor, Andrew E. Bradley, Suzanne F. Moss, Lorraine M. Loeb, Mark B. |
author_facet | Sandoval, Carolyn Walter, Stephen D. McGeer, Allison Simor, Andrew E. Bradley, Suzanne F. Moss, Lorraine M. Loeb, Mark B. |
author_sort | Sandoval, Carolyn |
collection | PubMed |
description | Limited data identify the risk factors for infection with Enterobacteriaceae resistant to third-generation cephalosporins among residents of long-term-care facilities. Using a nested case-control study design, nursing home residents with clinical isolates of Enterobacteriaceae resistant to third-generation cephalosporins were compared to residents with isolates of Enterobacteriaceae susceptible to third-generation cephalosporins. Data were collected on antimicrobial drug exposure 10 weeks before detection of the isolates, facility-level demographics, hygiene facilities, and staffing levels. Logistic regression models were built to adjust for confounding variables. Twenty-seven case-residents were identified and compared to 85 controls. Exposure to any cephalosporin (adjusted odds ratio [OR] 4.0, 95% confidence interval [CI] 1.2 to13.6) and log percentage of residents using gastrostomy tubes within the nursing home (adjusted OR 3.9, 95% CI 1.3 to 12.0) were associated with having a clinical isolate resistant to third-generation cephalosporins. |
format | Online Article Text |
id | pubmed-3323163 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-33231632012-04-17 Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins Sandoval, Carolyn Walter, Stephen D. McGeer, Allison Simor, Andrew E. Bradley, Suzanne F. Moss, Lorraine M. Loeb, Mark B. Emerg Infect Dis Research Limited data identify the risk factors for infection with Enterobacteriaceae resistant to third-generation cephalosporins among residents of long-term-care facilities. Using a nested case-control study design, nursing home residents with clinical isolates of Enterobacteriaceae resistant to third-generation cephalosporins were compared to residents with isolates of Enterobacteriaceae susceptible to third-generation cephalosporins. Data were collected on antimicrobial drug exposure 10 weeks before detection of the isolates, facility-level demographics, hygiene facilities, and staffing levels. Logistic regression models were built to adjust for confounding variables. Twenty-seven case-residents were identified and compared to 85 controls. Exposure to any cephalosporin (adjusted odds ratio [OR] 4.0, 95% confidence interval [CI] 1.2 to13.6) and log percentage of residents using gastrostomy tubes within the nursing home (adjusted OR 3.9, 95% CI 1.3 to 12.0) were associated with having a clinical isolate resistant to third-generation cephalosporins. Centers for Disease Control and Prevention 2004-06 /pmc/articles/PMC3323163/ /pubmed/15207056 http://dx.doi.org/10.3201/eid1006.030662 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Sandoval, Carolyn Walter, Stephen D. McGeer, Allison Simor, Andrew E. Bradley, Suzanne F. Moss, Lorraine M. Loeb, Mark B. Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins |
title | Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins |
title_full | Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins |
title_fullStr | Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins |
title_full_unstemmed | Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins |
title_short | Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins |
title_sort | nursing home residents and enterobacteriaceae resistant to third-generation cephalosporins |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323163/ https://www.ncbi.nlm.nih.gov/pubmed/15207056 http://dx.doi.org/10.3201/eid1006.030662 |
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