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Molecular Analysis of Plasmodium ovale Variants

Complete DNA sequences of the small subunit ribosomal RNA (SSUrRNA) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type Plasmodium ovale isolates from Southeast Asia and compared with GenBank-available data. Three different SSUrRNA sequences (P...

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Autores principales: Win, Thin Thida, Jalloh, Amadu, Tantular, Indah Setyawati, Tsuboi, Takafumi, Ferreira, Marcelo Urbano, Kimura, Masatsugu, Kawamoto, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323326/
https://www.ncbi.nlm.nih.gov/pubmed/15324543
http://dx.doi.org/10.3201/eid1007.030411
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author Win, Thin Thida
Jalloh, Amadu
Tantular, Indah Setyawati
Tsuboi, Takafumi
Ferreira, Marcelo Urbano
Kimura, Masatsugu
Kawamoto, Fumihiko
author_facet Win, Thin Thida
Jalloh, Amadu
Tantular, Indah Setyawati
Tsuboi, Takafumi
Ferreira, Marcelo Urbano
Kimura, Masatsugu
Kawamoto, Fumihiko
author_sort Win, Thin Thida
collection PubMed
description Complete DNA sequences of the small subunit ribosomal RNA (SSUrRNA) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type Plasmodium ovale isolates from Southeast Asia and compared with GenBank-available data. Three different SSUrRNA sequences (Pov 1–3) were found in each variant-type isolate, and two different SSUrRNA sequences (Poc 1–2) in each classic-type isolate. Pov 1–3 were closer to sequences previously found in the Cameroon and MAL/MAI isolates, whereas Poc 1–2 were closer to sequences previously found in two clones of the Nigerian I/CDC strain. The 3´ half of Pov 1–3 was identical to the partial sequence of the SSUrRNA gene from the London School (LS) strain. Results support grouping P. ovale into two groups, the classic type (including the Nigerian I/CDC strain) and the variant type (Cameroon, MAL/MAI, and LS isolates).
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spelling pubmed-33233262012-04-17 Molecular Analysis of Plasmodium ovale Variants Win, Thin Thida Jalloh, Amadu Tantular, Indah Setyawati Tsuboi, Takafumi Ferreira, Marcelo Urbano Kimura, Masatsugu Kawamoto, Fumihiko Emerg Infect Dis Research Complete DNA sequences of the small subunit ribosomal RNA (SSUrRNA) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type Plasmodium ovale isolates from Southeast Asia and compared with GenBank-available data. Three different SSUrRNA sequences (Pov 1–3) were found in each variant-type isolate, and two different SSUrRNA sequences (Poc 1–2) in each classic-type isolate. Pov 1–3 were closer to sequences previously found in the Cameroon and MAL/MAI isolates, whereas Poc 1–2 were closer to sequences previously found in two clones of the Nigerian I/CDC strain. The 3´ half of Pov 1–3 was identical to the partial sequence of the SSUrRNA gene from the London School (LS) strain. Results support grouping P. ovale into two groups, the classic type (including the Nigerian I/CDC strain) and the variant type (Cameroon, MAL/MAI, and LS isolates). Centers for Disease Control and Prevention 2004-07 /pmc/articles/PMC3323326/ /pubmed/15324543 http://dx.doi.org/10.3201/eid1007.030411 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Win, Thin Thida
Jalloh, Amadu
Tantular, Indah Setyawati
Tsuboi, Takafumi
Ferreira, Marcelo Urbano
Kimura, Masatsugu
Kawamoto, Fumihiko
Molecular Analysis of Plasmodium ovale Variants
title Molecular Analysis of Plasmodium ovale Variants
title_full Molecular Analysis of Plasmodium ovale Variants
title_fullStr Molecular Analysis of Plasmodium ovale Variants
title_full_unstemmed Molecular Analysis of Plasmodium ovale Variants
title_short Molecular Analysis of Plasmodium ovale Variants
title_sort molecular analysis of plasmodium ovale variants
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323326/
https://www.ncbi.nlm.nih.gov/pubmed/15324543
http://dx.doi.org/10.3201/eid1007.030411
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