Nosocomial Infection with Vancomycin-dependent Enterococci

We report three patients infected with unique strains of vancomycin-dependent enterococci. Two were first infected by genetically identical strains of vancomycin-resistant enterococci (VRE). All three patients had much greater exposure to vancomycin and third-generation cephalosporins than did two c...

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Autores principales: Tambyah, Paul A., Marx, John A., Maki, Dennis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323346/
https://www.ncbi.nlm.nih.gov/pubmed/15324549
http://dx.doi.org/10.3201/eid1007.030993
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author Tambyah, Paul A.
Marx, John A.
Maki, Dennis G.
author_facet Tambyah, Paul A.
Marx, John A.
Maki, Dennis G.
author_sort Tambyah, Paul A.
collection PubMed
description We report three patients infected with unique strains of vancomycin-dependent enterococci. Two were first infected by genetically identical strains of vancomycin-resistant enterococci (VRE). All three patients had much greater exposure to vancomycin and third-generation cephalosporins than did two control groups (patients infected with VRE and hospitalized patients without enterococcal infections). While antimicrobial pressure promotes nosocomial colonization by VRE, prolonged exposure to vancomycin may foster the transition from vancomycin resistance to dependence.
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spelling pubmed-33233462012-04-17 Nosocomial Infection with Vancomycin-dependent Enterococci Tambyah, Paul A. Marx, John A. Maki, Dennis G. Emerg Infect Dis Research We report three patients infected with unique strains of vancomycin-dependent enterococci. Two were first infected by genetically identical strains of vancomycin-resistant enterococci (VRE). All three patients had much greater exposure to vancomycin and third-generation cephalosporins than did two control groups (patients infected with VRE and hospitalized patients without enterococcal infections). While antimicrobial pressure promotes nosocomial colonization by VRE, prolonged exposure to vancomycin may foster the transition from vancomycin resistance to dependence. Centers for Disease Control and Prevention 2004-07 /pmc/articles/PMC3323346/ /pubmed/15324549 http://dx.doi.org/10.3201/eid1007.030993 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Tambyah, Paul A.
Marx, John A.
Maki, Dennis G.
Nosocomial Infection with Vancomycin-dependent Enterococci
title Nosocomial Infection with Vancomycin-dependent Enterococci
title_full Nosocomial Infection with Vancomycin-dependent Enterococci
title_fullStr Nosocomial Infection with Vancomycin-dependent Enterococci
title_full_unstemmed Nosocomial Infection with Vancomycin-dependent Enterococci
title_short Nosocomial Infection with Vancomycin-dependent Enterococci
title_sort nosocomial infection with vancomycin-dependent enterococci
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323346/
https://www.ncbi.nlm.nih.gov/pubmed/15324549
http://dx.doi.org/10.3201/eid1007.030993
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