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Alligators as West Nile Virus Amplifiers

Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >...

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Detalles Bibliográficos
Autores principales: Klenk, Kaci, Snow, Jamie, Morgan, Katrina, Bowen, Richard, Stephens, Michael, Foster, Falicia, Gordy, Paul, Beckett, Susan, Komar, Nicholas, Gubler, Duane, Bunning, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323409/
https://www.ncbi.nlm.nih.gov/pubmed/15663852
http://dx.doi.org/10.3201/eid1012.040264
Descripción
Sumario:Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >5.0 log(10) PFU/mL (a threshold considered infectious for Culex quinquefasciatus mosquitoes) for 1 to 8 days. Noninoculated tankmates also became infected. The viremia profiles and multiple routes of infection suggest alligators may play an important role in WNV transmission in areas with high population densities of juvenile alligators.