Alligators as West Nile Virus Amplifiers

Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >...

Descripción completa

Detalles Bibliográficos
Autores principales: Klenk, Kaci, Snow, Jamie, Morgan, Katrina, Bowen, Richard, Stephens, Michael, Foster, Falicia, Gordy, Paul, Beckett, Susan, Komar, Nicholas, Gubler, Duane, Bunning, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323409/
https://www.ncbi.nlm.nih.gov/pubmed/15663852
http://dx.doi.org/10.3201/eid1012.040264
_version_ 1782229193144139776
author Klenk, Kaci
Snow, Jamie
Morgan, Katrina
Bowen, Richard
Stephens, Michael
Foster, Falicia
Gordy, Paul
Beckett, Susan
Komar, Nicholas
Gubler, Duane
Bunning, Michel
author_facet Klenk, Kaci
Snow, Jamie
Morgan, Katrina
Bowen, Richard
Stephens, Michael
Foster, Falicia
Gordy, Paul
Beckett, Susan
Komar, Nicholas
Gubler, Duane
Bunning, Michel
author_sort Klenk, Kaci
collection PubMed
description Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >5.0 log(10) PFU/mL (a threshold considered infectious for Culex quinquefasciatus mosquitoes) for 1 to 8 days. Noninoculated tankmates also became infected. The viremia profiles and multiple routes of infection suggest alligators may play an important role in WNV transmission in areas with high population densities of juvenile alligators.
format Online
Article
Text
id pubmed-3323409
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-33234092012-04-18 Alligators as West Nile Virus Amplifiers Klenk, Kaci Snow, Jamie Morgan, Katrina Bowen, Richard Stephens, Michael Foster, Falicia Gordy, Paul Beckett, Susan Komar, Nicholas Gubler, Duane Bunning, Michel Emerg Infect Dis Research Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >5.0 log(10) PFU/mL (a threshold considered infectious for Culex quinquefasciatus mosquitoes) for 1 to 8 days. Noninoculated tankmates also became infected. The viremia profiles and multiple routes of infection suggest alligators may play an important role in WNV transmission in areas with high population densities of juvenile alligators. Centers for Disease Control and Prevention 2004-12 /pmc/articles/PMC3323409/ /pubmed/15663852 http://dx.doi.org/10.3201/eid1012.040264 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Klenk, Kaci
Snow, Jamie
Morgan, Katrina
Bowen, Richard
Stephens, Michael
Foster, Falicia
Gordy, Paul
Beckett, Susan
Komar, Nicholas
Gubler, Duane
Bunning, Michel
Alligators as West Nile Virus Amplifiers
title Alligators as West Nile Virus Amplifiers
title_full Alligators as West Nile Virus Amplifiers
title_fullStr Alligators as West Nile Virus Amplifiers
title_full_unstemmed Alligators as West Nile Virus Amplifiers
title_short Alligators as West Nile Virus Amplifiers
title_sort alligators as west nile virus amplifiers
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323409/
https://www.ncbi.nlm.nih.gov/pubmed/15663852
http://dx.doi.org/10.3201/eid1012.040264
work_keys_str_mv AT klenkkaci alligatorsaswestnilevirusamplifiers
AT snowjamie alligatorsaswestnilevirusamplifiers
AT morgankatrina alligatorsaswestnilevirusamplifiers
AT bowenrichard alligatorsaswestnilevirusamplifiers
AT stephensmichael alligatorsaswestnilevirusamplifiers
AT fosterfalicia alligatorsaswestnilevirusamplifiers
AT gordypaul alligatorsaswestnilevirusamplifiers
AT beckettsusan alligatorsaswestnilevirusamplifiers
AT komarnicholas alligatorsaswestnilevirusamplifiers
AT gublerduane alligatorsaswestnilevirusamplifiers
AT bunningmichel alligatorsaswestnilevirusamplifiers

Ejemplares similares