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Predicting outcomes of steady-state (13)C isotope tracing experiments using Monte Carlo sampling
BACKGROUND: Carbon-13 ((13)C) analysis is a commonly used method for estimating reaction rates in biochemical networks. The choice of carbon labeling pattern is an important consideration when designing these experiments. We present a novel Monte Carlo algorithm for finding the optimal substrate inp...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323462/ https://www.ncbi.nlm.nih.gov/pubmed/22289253 http://dx.doi.org/10.1186/1752-0509-6-9 |