Predicting outcomes of steady-state (13)C isotope tracing experiments using Monte Carlo sampling

BACKGROUND: Carbon-13 ((13)C) analysis is a commonly used method for estimating reaction rates in biochemical networks. The choice of carbon labeling pattern is an important consideration when designing these experiments. We present a novel Monte Carlo algorithm for finding the optimal substrate inp...

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Detalles Bibliográficos
Autores principales: Schellenberger, Jan, Zielinski, Daniel C, Choi, Wing, Madireddi, Sunthosh, Portnoy, Vasiliy, Scott, David A, Reed, Jennifer L, Osterman, Andrei L, Palsson, Bernhard ∅
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323462/
https://www.ncbi.nlm.nih.gov/pubmed/22289253
http://dx.doi.org/10.1186/1752-0509-6-9

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