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Effects of adenosine A(2A )receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice
BACKGROUND: Severe Clostridium difficile toxin-induced enteritis is characterized by exuberant intestinal tissue inflammation, epithelial disruption and diarrhea. Adenosine, through its action on the adenosine A(2A )receptor, prevents neutrophillic adhesion and oxidative burst and inhibits inflammat...
Autores principales: | Warren, Cirle Alcantara, Calabrese, Gina M, Li, Yuesheng, Pawlowski, Sean W, Figler, Robert A, Rieger, Jayson, Ernst, Peter B, Linden, Joel, Guerrant, Richard L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323464/ https://www.ncbi.nlm.nih.gov/pubmed/22264229 http://dx.doi.org/10.1186/1471-2334-12-13 |
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