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In Vitro and In Vivo Efficacy of Ether Lipid Edelfosine against Leishmania spp. and SbV-Resistant Parasites

BACKGROUND: The leishmaniases are a complex of neglected tropical diseases caused by more than 20 Leishmania parasite species, for which available therapeutic arsenal is scarce and unsatisfactory. Pentavalent antimonials (SbV) are currently the first-line pharmacologic therapy for leishmaniasis worl...

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Detalles Bibliográficos
Autores principales:	Varela-M, Rubén E., Villa-Pulgarin, Janny A., Yepes, Edward, Müller, Ingrid, Modolell, Manuel, Muñoz, Diana L., Robledo, Sara M., Muskus, Carlos E., López-Abán, Julio, Muro, Antonio, Vélez, Iván D., Mollinedo, Faustino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323514/ https://www.ncbi.nlm.nih.gov/pubmed/22506086 http://dx.doi.org/10.1371/journal.pntd.0001612

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