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A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity
Endogenous small molecule metabolites that regulate animal longevity are emerging as a novel means to influence health and life span. In C. elegans, bile acid-like steroids called the dafachronic acids (DAs) regulate developmental timing and longevity through the conserved nuclear hormone receptor D...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323522/ https://www.ncbi.nlm.nih.gov/pubmed/22505847 http://dx.doi.org/10.1371/journal.pbio.1001305 |