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Mutual Regulation of Bcl-2 Proteins Independent of the BH3 Domain as Shown by the BH3-Lacking Protein Bcl-x(AK)

The BH3 domain of Bcl-2 proteins was regarded as indispensable for apoptosis induction and for mutual regulation of family members. We recently described Bcl-x(AK), a proapoptotic splice product of the bcl-x gene, which lacks BH3 but encloses BH2, BH4 and a transmembrane domain. It remained however...

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Detalles Bibliográficos
Autores principales:	Plötz, Michael, Hossini, Amir M., Gillissen, Bernhard, Daniel, Peter T., Stockfleth, Eggert, Eberle, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323539/ https://www.ncbi.nlm.nih.gov/pubmed/22506026 http://dx.doi.org/10.1371/journal.pone.0034549

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