Cargando…

Insulinotropic Effect of the Non-Steroidal Compound STX in Pancreatic β-Cells

The non-steroidal compound STX modulates the hypothalamic control of core body temperature and energy homeostasis. The aim of this work was to study the potential effects of STX on pancreatic β-cell function. 1–10 nM STX produced an increase in glucose-induced insulin secretion in isolated islets fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ropero, Ana B., Alonso-Magdalena, Paloma, Soriano, Sergi, Juan-Picó, Pablo, Roepke, Troy A., Kelly, Martin J., Nadal, Ángel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323542/ https://www.ncbi.nlm.nih.gov/pubmed/22506040 http://dx.doi.org/10.1371/journal.pone.0034650

Ejemplares similares

Correction: Insulinotropic Effect of the Non-Steroidal Compound STX in Pancreatic β-Cells
por: Ropero, Ana B., et al.
Publicado: (2012)

Rapid Insulinotropic Action of Low Doses of Bisphenol-A on Mouse and Human Islets of Langerhans: Role of Estrogen Receptor β
por: Soriano, Sergi, et al.
Publicado: (2012)

Antidiabetic Actions of an Estrogen Receptor β Selective Agonist
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2013)

Glucose‐dependent insulinotropic polypeptide signaling in pancreatic β‐cells and adipocytes
por: McIntosh, Christopher HS, et al.
Publicado: (2012)

Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca(2+) Signals in Pancreatic α-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2005)

Screening of Relevant Metabolism-Disrupting Chemicals on Pancreatic β-Cells: Evaluation of Murine and Human In Vitro Models
por: Al-Abdulla, Ruba, et al.
Publicado: (2022)

The Estrogenic Effect of Bisphenol A Disrupts Pancreatic β-Cell Function In Vivo and Induces Insulin Resistance
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2006)

Pancreatic Insulin Content Regulation by the Estrogen Receptor ERα
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2008)

Bisphenol A Exposure during Pregnancy Disrupts Glucose Homeostasis in Mothers and Adult Male Offspring
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2010)

Mechanisms that Determine the Differential Stability of Stx(+) and Stx(−) Lysogens
por: Colon, Michael P., et al.
Publicado: (2016)

In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer
por: Stengel, C, et al.
Publicado: (2014)

Inhibitory Effects of Leptin on Pancreatic α-Cell Function
por: Tudurí, Eva, et al.
Publicado: (2009)

Cortistatin hyperpolarizes pancreatic beta cell membrane and reduces glucose-stimulated insulin secretion
por: Rafacho, Alex, et al.
Publicado: (2015)

Detection of stx(1) and stx(2) Genes in Pennsylvanian White-Tailed Deer
por: Kistler, Whitney M., et al.
Publicado: (2011)

Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice
por: McNichol, Beth A., et al.
Publicado: (2021)

Stevia Nonsweetener Fraction Displays an Insulinotropic Effect Involving Neurotransmission in Pancreatic Islets
por: Piovan, Silvano, et al.
Publicado: (2018)

Glucose Intolerance and Reduced Proliferation of Pancreatic β-Cells in Transgenic Pigs With Impaired Glucose-Dependent Insulinotropic Polypeptide Function
por: Renner, Simone, et al.
Publicado: (2010)

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells
por: Xu, Weiwei, et al.
Publicado: (2023)

Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice
por: Sheoran, Abhineet, et al.
Publicado: (2012)

Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca(2+) entry in mouse pancreatic β-cells
por: Villar-Pazos, Sabrina, et al.
Publicado: (2017)

Bisphenol A Regulates Sodium Ramp Currents in Mouse Dorsal Root Ganglion Neurons and Increases Nociception
por: Soriano, Sergi, et al.
Publicado: (2019)

Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin
por: Bunger, Joshua C., et al.
Publicado: (2015)

Improved Pancreatic β-Cell Function in Type 2 Diabetic Patients After Lifestyle-Induced Weight Loss Is Related to Glucose-Dependent Insulinotropic Polypeptide
por: Solomon, Thomas P.J., et al.
Publicado: (2010)

Promoter Sequence of Shiga Toxin 2 (Stx2) Is Recognized In Vivo, Leading to Production of Biologically Active Stx2
por: Bentancor, Leticia V., et al.
Publicado: (2013)

Identification and Characterization of ten Escherichia coli Strains Encoding Novel Shiga Toxin 2 Subtypes, Stx2n as Well as Stx2j, Stx2m, and Stx2o, in the United States
por: Lindsey, Rebecca L., et al.
Publicado: (2023)

New Stx2e Monoclonal Antibodies for Immunological Detection and Distinction of Stx2 Subtypes
por: Skinner, Craig, et al.
Publicado: (2015)

Differences in the Shiga Toxin (Stx) 2a Phage Regulatory Switch Region Influence Stx2 Localization and Virulence of Stx-Producing Escherichia coli in Mice
por: Atitkar, Rama R., et al.
Publicado: (2023)

Author Correction: Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca(2+) entry in mouse pancreatic β-cells
por: Villar-Pazos, Sabrina, et al.
Publicado: (2018)

Exploring the Effects of Metabolism-Disrupting Chemicals on Pancreatic α-Cell Viability, Gene Expression and Function: A Screening Testing Approach
por: Al-Abdulla, Ruba, et al.
Publicado: (2023)

Structure–Activity Relationship for the First-in-Class Clinical Steroid Sulfatase Inhibitor Irosustat (STX64, BN83495)
por: Woo, L W Lawrence, et al.
Publicado: (2011)

Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy
por: Fusi, L., et al.
Publicado: (2008)

Shiga Toxin (Stx) Type 1a Reduces the Oral Toxicity of Stx Type 2a
por: Russo, Lisa M., et al.
Publicado: (2016)

Characterisation of Glucose-Dependent Insulinotropic Polypeptide Receptor Antagonists in Rodent Pancreatic Beta Cells and Mice
por: Perry, RA, et al.
Publicado: (2019)

Insulinotropic Effect of S-Allyl Cysteine in Rat Pups
por: Lembede, Busisani W., et al.
Publicado: (2018)

Prenatal Exposure to BPA and Offspring Outcomes: The Diabesogenic Behavior of BPA
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2015)

SAT-715 Bisphenol-A Alters Pancreatic B-Cell Proliferation and Mass in an Estrogen Receptor Beta-Dependent Manner
por: Nadal, Angel, et al.
Publicado: (2020)

OR23-3 Differential Effects of Chronic Exposure to Bisphenol-A on Ion Channel Activity and Expression in Mouse Pancreatic Beta-Cells
por: Nadal, Angel, et al.
Publicado: (2019)

The Incretins and Pancreatic β-Cells: Use of Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Polypeptide to Cure Type 2 Diabetes Mellitus
por: Kim, Mi-Hyun, et al.
Publicado: (2010)

Glucose-dependent Insulinotropic Polypeptide (GIP) Resistance and β-cell Dysfunction Contribute to Hyperglycaemia in Acromegaly
por: Shekhawat, Vikram Singh, et al.
Publicado: (2019)

β-Catenin mediates glucose-dependent insulinotropic polypeptide increases in lysyl oxidase expression in osteoblasts()
por: Daley, Eileen J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lc88u8kp9u2vbnc3g2hk31sntp