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Nitroxyl (HNO) Stimulates Soluble Guanylyl Cyclase to Suppress Cardiomyocyte Hypertrophy and Superoxide Generation

BACKGROUND: New therapeutic targets for cardiac hypertrophy, an independent risk factor for heart failure and death, are essential. HNO is a novel redox sibling of NO• attracting considerable attention for the treatment of cardiovascular disorders, eliciting cGMP-dependent vasodilatation yet cGMP-in...

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Detalles Bibliográficos
Autores principales:	Lin, Eliane Q., Irvine, Jennifer C., Cao, Anh H., Alexander, Amy E., Love, Jane E., Patel, Ruchi, McMullen, Julie R., Kaye, David M., Kemp-Harper, Barbara K., Ritchie, Rebecca H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323591/ https://www.ncbi.nlm.nih.gov/pubmed/22506056 http://dx.doi.org/10.1371/journal.pone.0034892

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