Spherical Lactic Acid Bacteria Activate Plasmacytoid Dendritic Cells Immunomodulatory Function via TLR9-Dependent Crosstalk with Myeloid Dendritic Cells

Plasmacytoid dendritic cells (pDC) are a specialized sensor of viral and bacterial nucleic acids and a major producer of IFN-α that promotes host defense by priming both innate and acquired immune responses. Although synthetic Toll-like receptor (TLR) ligands, pathogenic bacteria and viruses activat...

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Detalles Bibliográficos
Autores principales: Jounai, Kenta, Ikado, Kumiko, Sugimura, Tetsu, Ano, Yasuhisa, Braun, Jonathan, Fujiwara, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323594/
https://www.ncbi.nlm.nih.gov/pubmed/22505996
http://dx.doi.org/10.1371/journal.pone.0032588

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