Cargando…

High-Level Expression of Notch1 Increased the Risk of Metastasis in T1 Stage Clear Cell Renal Cell Carcinoma

BACKGROUND: Although metastasis of clear cell renal cell carcinoma (ccRCC) is basically observed in late stage tumors, T1 stage metastasis of ccRCC can also be found with no definite molecular cause resulting inappropriate selection of surgery method and poor prognosis. Notch signaling is a conserve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ai, Qing, Ma, Xin, Huang, Qingbo, Liu, Shangwen, Shi, Taoping, Zhang, Chao, Zhu, Mingyang, Zhang, Yu, Wang, Baojun, Ni, Dong, Li, Hongzhao, Zheng, Tao, Zhang, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323638/ https://www.ncbi.nlm.nih.gov/pubmed/22506064 http://dx.doi.org/10.1371/journal.pone.0035022

Ejemplares similares

Overexpression of E2F1 Promotes Tumor Malignancy And Correlates with TNM Stages in Clear Cell Renal Cell Carcinoma
por: Ma, Xin, et al.
Publicado: (2013)

Hypoxia-induced overexpression of stanniocalcin-1 is associated with the metastasis of early stage clear cell renal cell carcinoma
por: Ma, Xin, et al.
Publicado: (2015)

Attenuation of Krüppel-Like Factor 4 Facilitates Carcinogenesis by Inducing G1/S Phase Arrest in Clear Cell Renal Cell Carcinoma
por: Song, Erlin, et al.
Publicado: (2013)

E2F3 upregulation promotes tumor malignancy through the transcriptional activation of HIF-2α in clear cell renal cell carcinoma
por: Gao, Yu, et al.
Publicado: (2016)

Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α
por: Fan, Yang, et al.
Publicado: (2016)

EFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma
por: Meng, Kun, et al.
Publicado: (2023)

Metastatic clear-cell renal cell carcinoma: a frequent NOTCH1 mutation predictive of response to anti-NOTCH1 CB-103 treatment
por: Bui, Thi Oanh, et al.
Publicado: (2023)

Prognostic Signatures and Therapeutic Value Based on the Notch Pathway in Renal Clear Cell Carcinoma
por: Li, Ziyao, et al.
Publicado: (2022)

Loss of cell division cycle-associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinoma
por: Huang, Xing, et al.
Publicado: (2022)

Notch 1 is a valuable therapeutic target against cell survival and proliferation in clear cell renal cell carcinoma
por: Zhuang, Zhiming, et al.
Publicado: (2017)

Renal Clear Cell Carcinoma and Tonsil Metastasis
por: Marcotullio, Dario, et al.
Publicado: (2013)

T1 Stage Clear Cell Renal Cell Carcinoma: A CT-Based Radiomics Nomogram to Estimate the Risk of Recurrence and Metastasis
por: Kang, Bing, et al.
Publicado: (2020)

A three-molecule score based on Notch pathway predicts poor prognosis in non-metastasis clear cell renal cell carcinoma
por: Liu, Zheng, et al.
Publicado: (2016)

FDX1 expression predicts favourable prognosis in clear cell renal cell carcinoma identified by bioinformatics and tissue microarray analysis
por: Huang, Xing, et al.
Publicado: (2022)

Overexpression of NEK2 is correlated with poor prognosis in human clear cell renal cell carcinoma
por: Wang, Chenfeng, et al.
Publicado: (2021)

Postoperative Adjuvant Sorafenib or Sunitinib for Nonmetastatic Renal Cell Carcinoma with Venous Tumor Thrombus: a Prospective Cohort Study
por: Gu, Liangyou, et al.
Publicado: (2017)

Identification of key genes involved in the metastasis of clear cell renal cell carcinoma
por: Wei, Wenhao, et al.
Publicado: (2019)

Down-Regulated miR-30a in Clear Cell Renal Cell Carcinoma Correlated with Tumor Hematogenous Metastasis by Targeting Angiogenesis-Specific DLL4
por: Huang, Qing Bo, et al.
Publicado: (2013)

KMT5A promotes metastasis of clear cell renal cell carcinoma through reducing cadherin-1 expression
por: Lin, Zhen-Zhong, et al.
Publicado: (2019)

Unexpected Gallbladder Metastasis of Clear Cell Renal Carcinoma
por: White, Ian, et al.
Publicado: (2019)

The Notch and TGF-β Signaling Pathways Contribute to the Aggressiveness of Clear Cell Renal Cell Carcinoma
por: Sjölund, Jonas, et al.
Publicado: (2011)

LncRNA MILIP links YBX1 to translational activation of Snai1 and promotes metastasis in clear cell renal cell carcinoma
por: Wang, Yanliang, et al.
Publicado: (2022)

Genomic Landscape of Chinese Clear Cell Renal Cell Carcinoma Patients With Venous Tumor Thrombus Identifies Chromosome 9 and 14 Deletions and Related Immunosuppressive Microenvironment
por: Niu, Shaoxi, et al.
Publicado: (2021)

Robotic-assisted laparoscopic pyeloplasty as management for recurrent ureteropelvic junction obstruction: a comparison study with primary pyeloplasty
por: Zhang, Peng, et al.
Publicado: (2020)

Silencing of lncRNA AFAP1-AS1 Inhibits Cell Growth and Metastasis in Clear Cell Renal Cell Carcinoma
por: Mu, Zhongyi, et al.
Publicado: (2019)

Identification of a Metastasis-Associated Gene Signature of Clear Cell Renal Cell Carcinoma
por: Gao, Suhua, et al.
Publicado: (2021)

Co-Expression Network Analysis Identified LTF in Association with Metastasis Risk and Prognosis in Clear Cell Renal Cell Carcinoma
por: Ni, Lihua, et al.
Publicado: (2020)

Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma
por: Hu, Junhui, et al.
Publicado: (2023)

Ubiquitin ligase SMURF1 functions as a prognostic marker and promotes growth and metastasis of clear cell renal cell carcinoma
por: Ke, Mang, et al.
Publicado: (2017)

The intrarenal landscape of T cell receptor repertoire in clear cell renal cell cancer
por: Zhang, Wei, et al.
Publicado: (2022)

Clival metastasis of renal clear cell carcinoma: Case report and literature review
por: Zhang, Wei-Qi, et al.
Publicado: (2018)

miR-155 regulates the proliferation and invasion of clear cell renal cell carcinoma cells by targeting E2F2
por: Gao, Yu, et al.
Publicado: (2016)

Thyroid metastasis as initial presentation of clear cell renal carcinoma
por: Ramírez-Plaza, César Pablo, et al.
Publicado: (2015)

Unilateral ovarian metastasis from renal clear cell carcinoma
por: Younes, Bencherifi, et al.
Publicado: (2023)

Alteration of ASIC1 expression in clear cell renal cell carcinoma
por: Li, Yan, et al.
Publicado: (2015)

A Notch signaling-related lncRNA signature for predicting prognosis and therapeutic response in clear cell renal cell carcinoma
por: Zhang, Lulu, et al.
Publicado: (2023)

α-1,2-Mannosidase MAN1C1 Inhibits Proliferation and Invasion of Clear Cell Renal Cell Carcinoma
por: Li, Haoming, et al.
Publicado: (2018)

SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma
por: Pu, Yan, et al.
Publicado: (2022)

Expression of CIDE proteins in clear cell renal cell carcinoma and their prognostic significance
por: Yu, Ming, et al.
Publicado: (2013)

MiR-506 Is Down-Regulated in Clear Cell Renal Cell Carcinoma and Inhibits Cell Growth and Metastasis via Targeting FLOT1
por: Yang, Feng-qiang, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2tjq8hb4m8fosfc4joqenel49b