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Stable Mutated tau441 Transfected SH-SY5Y Cells as Screening Tool for Alzheimer’s Disease Drug Candidates
The role of hyperphosphorylation of the microtubule-associated protein tau in the pathological processes of several neurodegenerative diseases is becoming better understood. Consequently, development of new compounds capable of preventing tau hyperphosphorylation is an increasingly hot topic. For th...
Autores principales: | Löffler, Tina, Flunkert, Stefanie, Taub, Nicole, Schofield, Emma L., Ward, Malcolm A., Windisch, Manfred, Hutter-Paier, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Humana Press Inc
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323815/ https://www.ncbi.nlm.nih.gov/pubmed/22351109 http://dx.doi.org/10.1007/s12031-012-9716-6 |
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