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Therapeutic potential of HIV protease-activable CASP3

Development of a therapeutic application of CASP3/caspase 3/CPP32, an executor of apoptosis, has been challenging because regulation of its activation is complicated. This study aimed to inhibit cancer cell growth and human immunodeficiency virus type 1 (HIV-1) propagation through a CASP3 mutant, CA...

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Detalles Bibliográficos
Autores principales: Miyauchi, Kosuke, Urano, Emiko, Takizawa, Mari, Ichikawa, Reiko, Komano, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323887/
https://www.ncbi.nlm.nih.gov/pubmed/22496955
http://dx.doi.org/10.1038/srep00359

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