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RASSF1A and the Taxol Response in Ovarian Cancer

The RASSF1A tumor suppressor gene is frequently inactivated by promoter methylation in human tumors. The RASSF1A protein forms an endogenous complex with tubulin and promotes the stabilization of microtubules. Loss of RASSF1A expression sensitizes cells to microtubule destabilizing stimuli. We have...

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Detalles Bibliográficos
Autores principales:	Kassler, Susannah, Donninger, Howard, Birrer, Michael J., Clark, Geoffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324163/ https://www.ncbi.nlm.nih.gov/pubmed/22548172 http://dx.doi.org/10.1155/2012/263267

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