Molecular Characterization of a Fully Human Chimeric T-Cell Antigen Receptor for Tumor-Associated Antigen EpCAM

The transduction of T cells to express chimeric T-cell antigen receptor (CAR) is an attractive strategy for adaptive immunotherapy for cancer, because the CAR can redirect the recognition specificity of T cells to tumor-associated antigens (TAAs) on the surface of target cells, thereby avoiding the...

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Detalles Bibliográficos
Autores principales: Shirasu, Naoto, Yamada, Hiromi, Shibaguchi, Hirotomo, Kuroki, Motomu, Kuroki, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324174/
https://www.ncbi.nlm.nih.gov/pubmed/22547929
http://dx.doi.org/10.1155/2012/853879

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