Circulating microRNAs: next-generation biomarkers for early lung cancer detection

Early diagnosis of lung cancer by low-dose computed tomography is an effective strategy to reduce cancer mortality in high-risk individuals. However, recruitment of at-risk individuals with asymptomatic lung cancer still remains challenging. We developed a minimal invasive serum test, based on the d...

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Detalles Bibliográficos
Autores principales: Bianchi, F, Nicassio, F, Veronesi, G, di Fiore, PP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2012
Materias:
Visions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324328/
https://www.ncbi.nlm.nih.gov/pubmed/22518197
http://dx.doi.org/10.3332/ecancer.2012.246
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author Bianchi, F
Nicassio, F
Veronesi, G
di Fiore, PP
author_facet Bianchi, F
Nicassio, F
Veronesi, G
di Fiore, PP
author_sort Bianchi, F
collection PubMed
description Early diagnosis of lung cancer by low-dose computed tomography is an effective strategy to reduce cancer mortality in high-risk individuals. However, recruitment of at-risk individuals with asymptomatic lung cancer still remains challenging. We developed a minimal invasive serum test, based on the detection of circulating microRNAs, which can identify at-risk individuals with asymptomatic early stage non-small cell lung carcinomas with 80% accuracy.
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spelling pubmed-33243282012-04-19 Circulating microRNAs: next-generation biomarkers for early lung cancer detection Bianchi, F Nicassio, F Veronesi, G di Fiore, PP Ecancermedicalscience Visions Early diagnosis of lung cancer by low-dose computed tomography is an effective strategy to reduce cancer mortality in high-risk individuals. However, recruitment of at-risk individuals with asymptomatic lung cancer still remains challenging. We developed a minimal invasive serum test, based on the detection of circulating microRNAs, which can identify at-risk individuals with asymptomatic early stage non-small cell lung carcinomas with 80% accuracy. Cancer Intelligence 2012-03-06 /pmc/articles/PMC3324328/ /pubmed/22518197 http://dx.doi.org/10.3332/ecancer.2012.246 Text en © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Visions
Bianchi, F
Nicassio, F
Veronesi, G
di Fiore, PP
Circulating microRNAs: next-generation biomarkers for early lung cancer detection
title Circulating microRNAs: next-generation biomarkers for early lung cancer detection
title_full Circulating microRNAs: next-generation biomarkers for early lung cancer detection
title_fullStr Circulating microRNAs: next-generation biomarkers for early lung cancer detection
title_full_unstemmed Circulating microRNAs: next-generation biomarkers for early lung cancer detection
title_short Circulating microRNAs: next-generation biomarkers for early lung cancer detection
title_sort circulating micrornas: next-generation biomarkers for early lung cancer detection
topic Visions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324328/
https://www.ncbi.nlm.nih.gov/pubmed/22518197
http://dx.doi.org/10.3332/ecancer.2012.246
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