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Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes

How various epigenetic mechanisms restrict chromatin plasticity to determine the stability of repressed genes is poorly understood. Nuclear transfer to Xenopus oocytes induces the transcriptional reactivation of previously silenced genes. Recent work suggests that it can be used to analyze the epige...

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Detalles Bibliográficos
Autores principales:	Pasque, Vincent, Halley-Stott, Richard P., Gillich, Astrid, Garrett, Nigel, Gurdon, John B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2011
Materias:	Extra View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324342/ https://www.ncbi.nlm.nih.gov/pubmed/22064467 http://dx.doi.org/10.4161/nucl.2.6.17799

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