Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease

Daptomycin is licensed in adults for the management of Staphylococcus aureus methicillin-resistant infections, including bone and skin complicated infections. We describe for the first time its use in a renal transplant recipient for Fabry-Anderson Disease with right heel osteomyelitis. The patient...

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Autores principales: Polilli, Ennio, Ursini, Tamara, Mazzotta, Elena, Sozio, Federica, Savini, Vincenzo, D'Antonio, Domenico, Barbato, Michelino, Consorte, Augusta, Parruti, Giustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324387/
https://www.ncbi.nlm.nih.gov/pubmed/22404900
http://dx.doi.org/10.1186/1476-0711-11-6
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author Polilli, Ennio
Ursini, Tamara
Mazzotta, Elena
Sozio, Federica
Savini, Vincenzo
D'Antonio, Domenico
Barbato, Michelino
Consorte, Augusta
Parruti, Giustino
author_facet Polilli, Ennio
Ursini, Tamara
Mazzotta, Elena
Sozio, Federica
Savini, Vincenzo
D'Antonio, Domenico
Barbato, Michelino
Consorte, Augusta
Parruti, Giustino
author_sort Polilli, Ennio
collection PubMed
description Daptomycin is licensed in adults for the management of Staphylococcus aureus methicillin-resistant infections, including bone and skin complicated infections. We describe for the first time its use in a renal transplant recipient for Fabry-Anderson Disease with right heel osteomyelitis. The patient was unresponsive to first-line Teicoplanin and second-line Tigecycline, whereas he was successfully treated with third-line Daptomycin monotherapy at 4 mg/Kg/qd for 4 weeks. Local debridement was performed in advance of each line of treatment.
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spelling pubmed-33243872012-04-12 Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease Polilli, Ennio Ursini, Tamara Mazzotta, Elena Sozio, Federica Savini, Vincenzo D'Antonio, Domenico Barbato, Michelino Consorte, Augusta Parruti, Giustino Ann Clin Microbiol Antimicrob Case Report Daptomycin is licensed in adults for the management of Staphylococcus aureus methicillin-resistant infections, including bone and skin complicated infections. We describe for the first time its use in a renal transplant recipient for Fabry-Anderson Disease with right heel osteomyelitis. The patient was unresponsive to first-line Teicoplanin and second-line Tigecycline, whereas he was successfully treated with third-line Daptomycin monotherapy at 4 mg/Kg/qd for 4 weeks. Local debridement was performed in advance of each line of treatment. BioMed Central 2012-03-11 /pmc/articles/PMC3324387/ /pubmed/22404900 http://dx.doi.org/10.1186/1476-0711-11-6 Text en Copyright ©2012 Polilli et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Polilli, Ennio
Ursini, Tamara
Mazzotta, Elena
Sozio, Federica
Savini, Vincenzo
D'Antonio, Domenico
Barbato, Michelino
Consorte, Augusta
Parruti, Giustino
Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease
title Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease
title_full Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease
title_fullStr Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease
title_full_unstemmed Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease
title_short Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease
title_sort successful salvage therapy with daptomycin for osteomyelitis caused by methicillin-resistant staphylococcus aureus in a renal transplant recipient with fabry-anderson disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324387/
https://www.ncbi.nlm.nih.gov/pubmed/22404900
http://dx.doi.org/10.1186/1476-0711-11-6
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