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Mixed Adjuvant Formulations Reveal a New Combination That Elicit Antibody Response Comparable to Freund's Adjuvants
Adjuvant formulations capable of inducing high titer and high affinity antibody responses would provide a major advance in the development of vaccines to viral infections such as HIV-1. Although oil-in-water emulsions, such as Freund's adjuvant (FCA/FIA), are known to be potent, their toxicity...
Autores principales: | Lai, Rachel P. J., Seaman, Michael S., Tonks, Paul, Wegmann, Frank, Seilly, David J., Frost, Simon D. W., LaBranche, Celia C., Montefiori, David C., Dey, Antu K., Srivastava, Indresh K., Sattentau, Quentin, Barnett, Susan W., Heeney, Jonathan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324409/ https://www.ncbi.nlm.nih.gov/pubmed/22509385 http://dx.doi.org/10.1371/journal.pone.0035083 |
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