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An Epithelial Serine Protease, AgESP, Is Required for Plasmodium Invasion in the Mosquito Anopheles gambiae

BACKGROUND: Plasmodium parasites need to cross the midgut and salivary gland epithelia to complete their life cycle in the mosquito. However, our understanding of the molecular mechanism and the mosquito genes that participate in this process is still very limited. METHODOLOGY/PRINCIPAL FINDINGS: We...

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Detalles Bibliográficos
Autores principales: Rodrigues, Janneth, Oliveira, Giselle A., Kotsyfakis, Michalis, Dixit, Rajnikant, Molina-Cruz, Alvaro, Jochim, Ryan, Barillas-Mury, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324419/
https://www.ncbi.nlm.nih.gov/pubmed/22509400
http://dx.doi.org/10.1371/journal.pone.0035210