Cargando…

Plant 45S rDNA Clusters Are Fragile Sites and Their Instability Is Associated with Epigenetic Alterations

Our previous study demonstrated that 45S ribosomal DNA (45S rDNA) clusters were chromosome fragile sites expressed spontaneously in Lolium. In this study, fragile phenotypes of 45S rDNA were observed under aphidicolin (APH) incubation in several plant species. Further actinomycin D (ActD) treatment...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Min, Li, Hui, Zhang, Lu, Gao, Fei, Wang, Pu, Hu, Yong, Yan, Shihan, Zhao, Lin, Zhang, Qi, Tan, Junjun, Liu, Xincheng, He, Shibin, Li, Lijia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324429/ https://www.ncbi.nlm.nih.gov/pubmed/22509394 http://dx.doi.org/10.1371/journal.pone.0035139

Ejemplares similares

45S rDNA Regions Are Chromosome Fragile Sites Expressed as Gaps In Vitro on Metaphase Chromosomes of Root-Tip Meristematic Cells in Lolium spp
por: Huang, Jing, et al.
Publicado: (2008)

Fragile Sites of ‘Valencia’ Sweet Orange (Citrus sinensis) Chromosomes Are Related with Active 45s rDNA
por: Lan, Hong, et al.
Publicado: (2016)

Genome Instability at Common Fragile Sites: Searching for the Cause of Their Instability
por: Franchitto, Annapaola
Publicado: (2013)

The Role of rDNA Clusters in Global Epigenetic Gene Regulation
por: Tchurikov, Nickolai A., et al.
Publicado: (2021)

DNA Instability at Chromosomal Fragile Sites in Cancer
por: Dillon, Laura W, et al.
Publicado: (2010)

Distribution of 45S rDNA sites in chromosomes of plants: Structural and evolutionary implications
por: Roa, Fernando, et al.
Publicado: (2012)

Comparative Chromosomal Localization of 45S and 5S rDNA Sites in 76 Purple-Fleshed Sweet Potato Cultivars
por: Su, Dan, et al.
Publicado: (2020)

Conserved Organisation of 45S rDNA Sites and rDNA Gene Copy Number among Major Clades of Early Land Plants
por: Rosato, Marcela, et al.
Publicado: (2016)

Genomic and Epigenomic Instability, Fragile Sites, Schizophrenia and Autism
por: Smith, Cassandra L., et al.
Publicado: (2010)

Fragile site instability: measuring more than breaks
por: Waisertreiger, Irina, et al.
Publicado: (2020)

The distribution of 45S rDNA sites in bird chromosomes suggests multiple evolutionary histories
por: Degrandi, Tiago Marafiga, et al.
Publicado: (2020)

BLM prevents instability of structure-forming DNA sequences at common fragile sites
por: Wang, Hailong, et al.
Publicado: (2018)

Deletion of the Tetrahymena thermophila rDNA replication fork barrier region disrupts macronuclear rDNA excision and creates a fragile site in the micronuclear genome
por: Yakisich, J. S., et al.
Publicado: (2006)

Editorial: Chromosomal fragile sites, genome instability and human diseases
por: Hu, Qing, et al.
Publicado: (2023)

Uneven Levels of 5S and 45S rDNA Site Number and Loci Variations across Wild Chrysanthemum Accessions
por: He, Jun, et al.
Publicado: (2022)

Uniqueness of the Gossypium mustelinum Genome Revealed by GISH and 45S rDNA FISH
por: Wu, Qiong, et al.
Publicado: (2013)

3D genome organization contributes to genome instability at fragile sites
por: Sarni, Dan, et al.
Publicado: (2020)

Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells
por: Arunkumar, Ganesan, et al.
Publicado: (2022)

Histone acetylation associated up-regulation of the cell wall related genes is involved in salt stress induced maize root swelling
por: Li, Hui, et al.
Publicado: (2014)

Methylation of 45S Ribosomal DNA (rDNA) Is Associated with Cancer and Aging in Humans
por: Shao, Fengqing, et al.
Publicado: (2021)

Randomly Detected Genetically Modified (GM) Maize (Zea mays L.) near a Transport Route Revealed a Fragile 45S rDNA Phenotype
por: Waminal, Nomar Espinosa, et al.
Publicado: (2013)

Physical localization of 45S rDNA in Cymbopogon and the analysis of differential distribution of rDNA in homologous chromosomes of Cymbopogon winterianus
por: Thakur, Shivangi, et al.
Publicado: (2021)

Secondary structure formation and DNA instability at fragile site FRA16B
por: Burrow, Allison A., et al.
Publicado: (2010)

Updating the mechanisms of common fragile site instability: how to reconcile the different views?
por: Le Tallec, Benoît, et al.
Publicado: (2014)

Chromosomal Instability at Fragile Sites in Blue Foxes, Silver Foxes, and Their Interspecific Hybrids
por: Kuchta-Gładysz, Marta, et al.
Publicado: (2021)

Comparative genetic analysis of the 45S rDNA intergenic spacers from three Saccharum species
por: Huang, Yongji, et al.
Publicado: (2017)

Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation
por: Zhou, Hong, et al.
Publicado: (2016)

FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
por: Fernandes, Philippe, et al.
Publicado: (2021)

Chromatin-Specific Regulation of Mammalian rDNA Transcription by Clustered TTF-I Binding Sites
por: Diermeier, Sarah D., et al.
Publicado: (2013)

Chromosomal Locations of 5S and 45S rDNA in Gossypium Genus and Its Phylogenetic Implications Revealed by FISH
por: Gan, Yimei, et al.
Publicado: (2013)

Repetitive Fragile Sites: Centromere Satellite DNA as a Source of Genome Instability in Human Diseases
por: Black, Elizabeth M., et al.
Publicado: (2018)

Comparative Analysis of Genome-Wide Chromosomal Histone Modification Patterns in Maize Cultivars and Their Wild Relatives
por: He, Shibin, et al.
Publicado: (2014)

Contrasting patterns of the 5S and 45S rDNA evolutions in the Byblis liniflora complex (Byblidaceae)
por: Fukushima, Kenji, et al.
Publicado: (2010)

Inhibition of DNA Methylation Alters Chromatin Organization, Nuclear Positioning and Activity of 45S rDNA Loci in Cycling Cells of Q. robur
por: Bočkor, Vedrana Vičić, et al.
Publicado: (2014)

Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies
por: Ruiz-Herrera, Aurora, et al.
Publicado: (2007)

Fragile Site Instability in Saccharomyces cerevisiae Causes Loss of Heterozygosity by Mitotic Crossovers and Break-Induced Replication
por: Rosen, Danielle M., et al.
Publicado: (2013)

High and uneven levels of 45S rDNA site-number variation across wild populations of a diploid plant genus (Anacyclus, Asteraceae)
por: Rosato, Marcela, et al.
Publicado: (2017)

Common fragile sites: protection and repair
por: Li, Shibo, et al.
Publicado: (2020)

Homology-dependent repair is involved in 45S rDNA loss in plant CAF-1 mutants
por: Muchová, Veronika, et al.
Publicado: (2015)

Zebularine induces enzymatic DNA–protein crosslinks in 45S rDNA heterochromatin of Arabidopsis nuclei
por: Prochazkova, Klara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_uc8k3624ej36bel88gg9l1fr65