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Prevention of Wear Particle-Induced Osteolysis by a Novel V-ATPase Inhibitor Saliphenylhalamide through Inhibition of Osteoclast Bone Resorption

Wear particle-induced peri-implant loosening (Aseptic prosthetic loosening) is one of the most common causes of total joint arthroplasty. It is well established that extensive bone destruction (osteolysis) by osteoclasts is responsible for wear particle-induced peri-implant loosening. Thus, inhibiti...

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Detalles Bibliográficos
Autores principales:	Qin, An, Cheng, Tak S., Lin, Zhen, Cao, Lei, Chim, Shek M., Pavlos, Nathan J., Xu, Jiake, Zheng, Ming Hao, Dai, Ke Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324493/ https://www.ncbi.nlm.nih.gov/pubmed/22509274 http://dx.doi.org/10.1371/journal.pone.0034132

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