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Chitosan-Graft-Branched Polyethylenimine Copolymers: Influence of Degree of Grafting on Transfection Behavior

BACKGROUND: Successful non-viral gene delivery currently requires compromises to achieve useful transfection levels while minimizing toxicity. Despite high molecular weight (MW) branched polyethylenimine (bPEI) is considered the gold standard polymeric transfectant, it suffers from high cytotoxicity...

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Detalles Bibliográficos
Autores principales: Pezzoli, Daniele, Olimpieri, Francesca, Malloggi, Chiara, Bertini, Sabrina, Volonterio, Alessandro, Candiani, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324502/
https://www.ncbi.nlm.nih.gov/pubmed/22509349
http://dx.doi.org/10.1371/journal.pone.0034711