Dissection of Pol II Trigger Loop Function and Pol II Activity–Dependent Control of Start Site Selection In Vivo

Structural and biochemical studies have revealed the importance of a conserved, mobile domain of RNA Polymerase II (Pol II), the Trigger Loop (TL), in substrate selection and catalysis. The relative contributions of different residues within the TL to Pol II function and how Pol II activity defects...

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Detalles Bibliográficos
Autores principales: Kaplan, Craig D., Jin, Huiyan, Zhang, Ivan Liang, Belyanin, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325174/
https://www.ncbi.nlm.nih.gov/pubmed/22511879
http://dx.doi.org/10.1371/journal.pgen.1002627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325174/
https://www.ncbi.nlm.nih.gov/pubmed/22511879
http://dx.doi.org/10.1371/journal.pgen.1002627

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