Cargando…
Transcriptional Regulation of Rod Photoreceptor Homeostasis Revealed by In Vivo NRL Targetome Analysis
A stringent control of homeostasis is critical for functional maintenance and survival of neurons. In the mammalian retina, the basic motif leucine zipper transcription factor NRL determines rod versus cone photoreceptor cell fate and activates the expression of many rod-specific genes. Here, we rep...
Autores principales: | Hao, Hong, Kim, Douglas S., Klocke, Bernward, Johnson, Kory R., Cui, Kairong, Gotoh, Norimoto, Zang, Chongzhi, Gregorski, Janina, Gieser, Linn, Peng, Weiqun, Fann, Yang, Seifert, Martin, Zhao, Keji, Swaroop, Anand |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325202/ https://www.ncbi.nlm.nih.gov/pubmed/22511886 http://dx.doi.org/10.1371/journal.pgen.1002649 |
Ejemplares similares
-
Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL
por: Zelinger, Lina, et al.
Publicado: (2017) -
Nrl:CreERT2 mouse model to induce mosaic gene expression in rod photoreceptors
por: Thorson, Molly T., et al.
Publicado: (2023) -
Nrl Is Dispensable for Specification of Rod Photoreceptors in Adult Zebrafish Despite Its Deeply Conserved Requirement Earlier in Ontogeny
por: Oel, A. Phillip, et al.
Publicado: (2020) -
Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration
por: Liu, Fei, et al.
Publicado: (2022) -
Photoreceptors of Nrl
(−/−) Mice Coexpress Functional S- and M-cone Opsins Having Distinct Inactivation Mechanisms
por: Nikonov, Sergei S., et al.
Publicado: (2005)