Mutations in MITF and PAX3 Cause “Splashed White” and Other White Spotting Phenotypes in Horses

During fetal development neural-crest-derived melanoblasts migrate across the entire body surface and differentiate into melanocytes, the pigment-producing cells. Alterations in this precisely regulated process can lead to white spotting patterns. White spotting patterns in horses are a complex trai...

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Detalles Bibliográficos
Autores principales: Hauswirth, Regula, Haase, Bianca, Blatter, Marlis, Brooks, Samantha A., Burger, Dominik, Drögemüller, Cord, Gerber, Vincent, Henke, Diana, Janda, Jozef, Jude, Rony, Magdesian, K. Gary, Matthews, Jacqueline M., Poncet, Pierre-André, Svansson, Vilhjálmur, Tozaki, Teruaki, Wilkinson-White, Lorna, Penedo, M. Cecilia T., Rieder, Stefan, Leeb, Tosso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325211/
https://www.ncbi.nlm.nih.gov/pubmed/22511888
http://dx.doi.org/10.1371/journal.pgen.1002653

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