Beta-Catenin Phosphorylated at Threonine 120 Antagonizes Generation of Active Beta-Catenin by Spatial Localization in trans-Golgi Network

The stability and subcellular localization of beta-catenin, a protein that plays a major role in cell adhesion and proliferation, is tightly regulated by multiple signaling pathways. While aberrant activation of beta-catenin signaling has been implicated in cancers, the biochemical identity of trans...

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Detalles Bibliográficos
Autores principales: Du, Cheng, Zhang, Chuanyou, Li, Zhuo, Biswas, Md. Helal Uddin, Balaji, K. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325232/
https://www.ncbi.nlm.nih.gov/pubmed/22511927
http://dx.doi.org/10.1371/journal.pone.0033830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325232/
https://www.ncbi.nlm.nih.gov/pubmed/22511927
http://dx.doi.org/10.1371/journal.pone.0033830

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