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BRCA1-IRIS Overexpression Promotes Formation of Aggressive Breast Cancers

INTRODUCTION: Women with HER2(+) or triple negative/basal-like (TN/BL) breast cancers succumb to their cancer rapidly due, in part to acquired Herceptin resistance and lack of TN/BL-targeted therapies. BRCA1-IRIS is a recently discovered, 1399 residue, BRCA1 locus alternative product, which while sh...

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Detalles Bibliográficos
Autores principales: Shimizu, Yoshiko, Luk, Hugh, Horio, David, Miron, Penelope, Griswold, Michael, Iglehart, Dirk, Hernandez, Brenda, Killeen, Jeffrey, ElShamy, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325250/
https://www.ncbi.nlm.nih.gov/pubmed/22511931
http://dx.doi.org/10.1371/journal.pone.0034102

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