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BRCA1-IRIS Overexpression Promotes Formation of Aggressive Breast Cancers
INTRODUCTION: Women with HER2(+) or triple negative/basal-like (TN/BL) breast cancers succumb to their cancer rapidly due, in part to acquired Herceptin resistance and lack of TN/BL-targeted therapies. BRCA1-IRIS is a recently discovered, 1399 residue, BRCA1 locus alternative product, which while sh...
Autores principales: | Shimizu, Yoshiko, Luk, Hugh, Horio, David, Miron, Penelope, Griswold, Michael, Iglehart, Dirk, Hernandez, Brenda, Killeen, Jeffrey, ElShamy, Wael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325250/ https://www.ncbi.nlm.nih.gov/pubmed/22511931 http://dx.doi.org/10.1371/journal.pone.0034102 |
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