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Excitability and Synaptic Alterations in the Cerebellum of APP/PS1 Mice

In Alzheimer's disease (AD), the severity of cognitive symptoms is better correlated with the levels of soluble amyloid-beta (Aβ) rather than with the deposition of fibrillar Aβ in amyloid plaques. In APP/PS1 mice, a murine model of AD, at 8 months of age the cerebellum is devoid of fibrillar A...

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Detalles Bibliográficos
Autores principales:	Hoxha, Eriola, Boda, Enrica, Montarolo, Francesca, Parolisi, Roberta, Tempia, Filippo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325253/ https://www.ncbi.nlm.nih.gov/pubmed/22511962 http://dx.doi.org/10.1371/journal.pone.0034726

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