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Analyses of the Large Subunit Histidine-Rich Motif Expose an Alternative Proton Transfer Pathway in [NiFe] Hydrogenases

A highly conserved histidine-rich region with unknown function was recognized in the large subunit of [NiFe] hydrogenases. The HxHxxHxxHxH sequence occurs in most membrane-bound hydrogenases, but only two of these histidines are present in the cytoplasmic ones. Site-directed mutagenesis of the His-r...

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Detalles Bibliográficos
Autores principales: Szőri-Dorogházi, Emma, Maróti, Gergely, Szőri, Milán, Nyilasi, Andrea, Rákhely, Gábor, Kovács, Kornél L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325256/
https://www.ncbi.nlm.nih.gov/pubmed/22511957
http://dx.doi.org/10.1371/journal.pone.0034666