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A Directed RNAi Screen Based on Larval Growth Arrest Reveals New Modifiers of C. elegans Insulin Signaling

Genes regulating Caenorhabditis elegans insulin/IGF signaling (IIS) have largely been identified on the basis of their involvement in dauer development or longevity. A third IIS phenotype is the first larval stage (L1) diapause, which is also influenced by asna-1, a regulator of DAF-28/insulin secre...

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Detalles Bibliográficos
Autores principales:	Billing, Ola, Natarajan, Balasubramanian, Mohammed, Ateequrrahman, Naredi, Peter, Kao, Gautam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325266/ https://www.ncbi.nlm.nih.gov/pubmed/22511947 http://dx.doi.org/10.1371/journal.pone.0034507

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