Focused Examination of the Intestinal lamina Propria Yields Greater Molecular Insight into Mechanisms Underlying SIV Induced Immune Dysfunction

BACKGROUND: The Gastrointestinal (GI) tract is critical to AIDS pathogenesis as it is the primary site for viral transmission and a major site of viral replication and CD4(+) T cell destruction. Consequently GI disease, a major complication of HIV/SIV infection can facilitate translocation of lumena...

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Detalles Bibliográficos
Autores principales: Mohan, Mahesh, Kaushal, Deepak, Aye, Pyone P., Alvarez, Xavier, Veazey, Ronald S., Lackner, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325268/
https://www.ncbi.nlm.nih.gov/pubmed/22511950
http://dx.doi.org/10.1371/journal.pone.0034561

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