Cargando…
A benchmarked protein microarray-based platform for the identification of novel low-affinity extracellular protein interactions
Low-affinity extracellular protein interactions are critical for cellular recognition processes, but existing methods to detect them are limited in scale, making genome-wide interaction screens technically challenging. To address this, we report here the miniaturization of the AVEXIS (avidity-based...
Autores principales: | Sun, Yi, Gallagher-Jones, Marcus, Barker, Colin, Wright, Gavin J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325482/ https://www.ncbi.nlm.nih.gov/pubmed/22342946 http://dx.doi.org/10.1016/j.ab.2012.01.034 |
Ejemplares similares
-
High-Content Imaging for Large-Scale Detection of Low-Affinity
Extracellular Protein Interactions
por: Wood, Laura, et al.
Publicado: (2019) -
Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction
por: Lee, Jung-Rok, et al.
Publicado: (2016) -
Avidity-based Extracellular Interaction Screening (AVEXIS) for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions
por: Kerr, Jason S., et al.
Publicado: (2012) -
Rapid and sensitive large-scale screening of low affinity extracellular receptor protein interactions by using reaction induced inhibition of Gaussia luciferase
por: Galaway, Francis, et al.
Publicado: (2020) -
Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers
por: Martin, Jennifer A., et al.
Publicado: (2016)