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Regulation of APC/C(Cdc20) activity by RASSF1A–APC/C(Cdc20) circuitry

RASSF1A is a key tumor-suppressor gene that is often inactivated in a wide variety of solid tumors. Studies have illustrated that RASSF1A plays vital roles in the regulation of cell-cycle progression and functions as a guardian of mitosis. Nevertheless, the precise mechanism of RASSF1A-dependent reg...

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Detalles Bibliográficos
Autores principales:	Chow, C, Wong, N, Pagano, M, Lun, S W-M, Nakayama, K-I, Nakayama, K, Lo, K-W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325600/ https://www.ncbi.nlm.nih.gov/pubmed/21874044 http://dx.doi.org/10.1038/onc.2011.372

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