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Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis
A 73-year-old woman underwent vitrectomy and intravitreal triamcinolone acetonide (IVTA) of the right eye and cataract surgery with IVTA of the left eye, for bilateral diabetic macular edema. The patient presented with visual loss in both eyes three-months postoperatively. The fundoscopic examinatio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Ophthalmological Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325623/ https://www.ncbi.nlm.nih.gov/pubmed/22511845 http://dx.doi.org/10.3341/kjo.2012.26.2.151 |
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author | Cho, Won Bin Kim, Hyung Chan Moon, Jun Woong |
author_facet | Cho, Won Bin Kim, Hyung Chan Moon, Jun Woong |
author_sort | Cho, Won Bin |
collection | PubMed |
description | A 73-year-old woman underwent vitrectomy and intravitreal triamcinolone acetonide (IVTA) of the right eye and cataract surgery with IVTA of the left eye, for bilateral diabetic macular edema. The patient presented with visual loss in both eyes three-months postoperatively. The fundoscopic examination revealed white-yellow, necrotic peripheral lesions in the superotemporal quadrant of both eyes. Although bilateral acute retinal necrosis was suspected, azotemia resulting from diabetic nephropathy limited the use of acyclovir. Antiviral treatment was not started. A sample of the aqueous humor for polymerase chain reaction (PCR) analysis was obtained. One week later, the PCR results indicated the presence of cytomegalovirus (CMV). Since the retinal lesions did not progress and did not threaten the macula, the patient was followed without treatment for CMV. The retinal lesions progressively regressed and completely resolved in both eyes by six months of follow-up. Patients with IVTA-induced CMV retinitis may not require systemic treatment with ganciclovir. |
format | Online Article Text |
id | pubmed-3325623 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Ophthalmological Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-33256232012-04-17 Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis Cho, Won Bin Kim, Hyung Chan Moon, Jun Woong Korean J Ophthalmol Case Report A 73-year-old woman underwent vitrectomy and intravitreal triamcinolone acetonide (IVTA) of the right eye and cataract surgery with IVTA of the left eye, for bilateral diabetic macular edema. The patient presented with visual loss in both eyes three-months postoperatively. The fundoscopic examination revealed white-yellow, necrotic peripheral lesions in the superotemporal quadrant of both eyes. Although bilateral acute retinal necrosis was suspected, azotemia resulting from diabetic nephropathy limited the use of acyclovir. Antiviral treatment was not started. A sample of the aqueous humor for polymerase chain reaction (PCR) analysis was obtained. One week later, the PCR results indicated the presence of cytomegalovirus (CMV). Since the retinal lesions did not progress and did not threaten the macula, the patient was followed without treatment for CMV. The retinal lesions progressively regressed and completely resolved in both eyes by six months of follow-up. Patients with IVTA-induced CMV retinitis may not require systemic treatment with ganciclovir. The Korean Ophthalmological Society 2012-04 2012-03-22 /pmc/articles/PMC3325623/ /pubmed/22511845 http://dx.doi.org/10.3341/kjo.2012.26.2.151 Text en © 2012 The Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Cho, Won Bin Kim, Hyung Chan Moon, Jun Woong Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis |
title | Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis |
title_full | Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis |
title_fullStr | Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis |
title_full_unstemmed | Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis |
title_short | Spontaneous Resolution of Intravitreal Steroid-Induced Bilateral Cytomegalovirus Retinitis |
title_sort | spontaneous resolution of intravitreal steroid-induced bilateral cytomegalovirus retinitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325623/ https://www.ncbi.nlm.nih.gov/pubmed/22511845 http://dx.doi.org/10.3341/kjo.2012.26.2.151 |
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