Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS

BACKGOUND: Amyotrophic lateral sclerosis (ALS) is progressive neurodegenerative disease characterized by the loss of motor function. Several ALS genes have been identified as their mutations can lead to familial ALS, including the recently reported RNA-binding protein fused in sarcoma (Fus). However...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Ruohan, Liu, Yajuan, Yang, Liuqing, Gal, Jozsef, Zhu, Haining, Jia, Jianhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325858/
https://www.ncbi.nlm.nih.gov/pubmed/22443542
http://dx.doi.org/10.1186/1750-1326-7-10

Ejemplares similares

Ejemplares similares