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Crucial Role of Heme Oxygenase-1 on the Sensitivity of Cholangiocarcinoma Cells to Chemotherapeutic Agents
Cancer cells acquire drug resistance via various mechanisms including enhanced cellular cytoprotective and antioxidant activities. Heme oxygenase-1 (HO-1) is a key enzyme exerting potent cytoprotection, cell proliferation and drug resistance. We aimed to investigate roles of HO-1 in human cholangioc...
Autores principales: | Kongpetch, Sarinya, Kukongviriyapan, Veerapol, Prawan, Auemduan, Senggunprai, Laddawan, Kukongviriyapan, Upa, Buranrat, Benjaporn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325916/ https://www.ncbi.nlm.nih.gov/pubmed/22514698 http://dx.doi.org/10.1371/journal.pone.0034994 |
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