Multistep Ion Channel Remodeling and Lethal Arrhythmia Precede Heart Failure in a Mouse Model of Inherited Dilated Cardiomyopathy

BACKGROUND: Patients with inherited dilated cardiomyopathy (DCM) frequently die with severe heart failure (HF) or die suddenly with arrhythmias, although these symptoms are not always observed at birth. It remains unclear how and when HF and arrhythmogenic changes develop in these DCM mutation carri...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Takeshi, Shioya, Takao, Murayama, Takashi, Sugihara, Masami, Odagiri, Fuminori, Nakazato, Yuji, Nishizawa, Hiroto, Chugun, Akihito, Sakurai, Takashi, Daida, Hiroyuki, Morimoto, Sachio, Kurebayashi, Nagomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325934/
https://www.ncbi.nlm.nih.gov/pubmed/22514734
http://dx.doi.org/10.1371/journal.pone.0035353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325934/
https://www.ncbi.nlm.nih.gov/pubmed/22514734
http://dx.doi.org/10.1371/journal.pone.0035353

Ejemplares similares